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NS-11394 is a drug which acts as a subtype-selective positive allosteric modulator at GABAA receptors, with selectivity for the α3 and α5 subtypes.[1][2] It has been researched as an analgesic for use in chronic or neuropathic pain.[3]
References
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| Monoaminergics |
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| Ion channel blockers |
- Anticonvulsants (e.g., gabapentin, pregabalin, carbamazepine, oxcarbazepine, lacosamide, lamotrigine)
- Local anesthetics (e.g., lidocaine)
- Mexiletine
- TCAs (e.g., amitriptyline, nortriptyline, desipramine)
- Ziconotide
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| Others |
- Alpha lipoic acid
- Benfotiamine
- Botulinum toxin A
- Bupropion
- Cannabinoids (e.g., cannabis, dronabinol, nabilone)
- NMDAR antagonists (e.g., ketamine, dextromethorphan, methadone)
- Opioids (e.g., hydrocodone, morphine, oxycodone, methadone, buprenorphine, tramadol, tapentadol)
- Sodium oxybate (GHB)
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| Alcohols |
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| Barbiturates |
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| Benzodiazepines |
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| Carbamates |
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| Flavonoids |
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| Imidazoles |
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| Kava constituents |
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| Monoureides |
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| Neuroactive steroids |
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| Nonbenzodiazepines |
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| Phenols |
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| Piperidinediones |
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| Pyrazolopyridines |
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| Quinazolinones |
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| Volatiles/gases |
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| Others/unsorted |
- 3-Hydroxybutanal
- α-EMTBL
- AA-29504
- Avermectins (e.g., ivermectin)
- Bromide compounds (e.g., lithium bromide, potassium bromide, sodium bromide)
- Carbamazepine
- Chloralose
- Chlormezanone
- Clomethiazole
- DEABL
- Dihydroergolines (e.g., dihydroergocryptine, dihydroergosine, dihydroergotamine, ergoloid (dihydroergotoxine))
- DS2
- Efavirenz
- Etazepine
- Etifoxine
- Fenamates (e.g., flufenamic acid, mefenamic acid, niflumic acid, tolfenamic acid)
- Fluoxetine
- Flupirtine
- Hopantenic acid
- Lanthanum
- Lavender oil
- Lignans (e.g., 4-O-methylhonokiol, honokiol, magnolol, obovatol)
- Loreclezole
- Menthyl isovalerate (validolum)
- Monastrol
- Niacin
- Nicotinamide (niacinamide)
- Org 25,435
- Phenytoin
- Propanidid
- Retigabine (ezogabine)
- Safranal
- Seproxetine
- Stiripentol
- Sulfonylalkanes (e.g., sulfonmethane (sulfonal), tetronal, trional)
- Terpenoids (e.g., borneol)
- Topiramate
- Valerian constituents (e.g., isovaleric acid, isovaleramide, valerenic acid, valerenol)
- Unsorted benzodiazepine site PAMs: MRK-409 (MK-0343)
- TCS-1105
- TCS-1205
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- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
