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Flutemazepam[1] was developed at a team at Stabilimenti Chimici Farmaceutici Riuniti SpA in the mid 1970s. Is a drug which is a 3-hydroxy benzodiazepine derivative and an analogue of temazepam that has hypnotic, sedative, amnesiac, anxiolytic, anticonvulsant and skeletal muscle relaxant properties. It is most closely related in structure to temazepam and is indicated for the treatment of severe insomnia.[2] Flutemazepam has properties similar to temazepam, and it has been found to be very effective for the treatment of severe states of anxiety, panic attacks, and severe insomnia.[3]
See also
References
- ↑ GB Patent 1431282 - BENZODIAZEPINE COMPOUNDS FOR THEREPEUTICAL USE
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ Ian K.M. Morton, Judith M. Hall. Concise Dictionary of Pharmacological agents. Springer, 1999. ISBN 0-7514-0499-3, ISBN 978-0-7514-0499-9
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Alcohols |
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Barbiturates |
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Benzodiazepines |
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Carbamates |
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Flavonoids |
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Imidazoles |
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Kava constituents |
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Monoureides |
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Neuroactive steroids |
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Nonbenzodiazepines |
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Phenols |
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Piperidinediones |
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Pyrazolopyridines |
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Quinazolinones |
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Volatiles/gases |
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Others/unsorted |
- 3-Hydroxybutanal
- α-EMTBL
- AA-29504
- Avermectins (e.g., ivermectin)
- Bromide compounds (e.g., lithium bromide, potassium bromide, sodium bromide)
- Carbamazepine
- Chloralose
- Chlormezanone
- Clomethiazole
- DEABL
- Dihydroergolines (e.g., dihydroergocryptine, dihydroergosine, dihydroergotamine, ergoloid (dihydroergotoxine))
- DS2
- Efavirenz
- Etazepine
- Etifoxine
- Fenamates (e.g., flufenamic acid, mefenamic acid, niflumic acid, tolfenamic acid)
- Fluoxetine
- Flupirtine
- Hopantenic acid
- Lanthanum
- Lavender oil
- Lignans (e.g., 4-O-methylhonokiol, honokiol, magnolol, obovatol)
- Loreclezole
- Menthyl isovalerate (validolum)
- Monastrol
- Niacin
- Nicotinamide (niacinamide)
- Org 25,435
- Phenytoin
- Propanidid
- Retigabine (ezogabine)
- Safranal
- Seproxetine
- Stiripentol
- Sulfonylalkanes (e.g., sulfonmethane (sulfonal), tetronal, trional)
- Terpenoids (e.g., borneol)
- Topiramate
- Valerian constituents (e.g., isovaleric acid, isovaleramide, valerenic acid, valerenol)
- Unsorted benzodiazepine site PAMs: MRK-409 (MK-0343)
- TCS-1105
- TCS-1205
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