Alphacetylmethadol

Alphacetylmethadol
	File:Alphacetylmethadol.svg
Systematic (IUPAC) name
	[(3R,6R)-6-dimethylamino-4,4-di(phenyl)heptan-3-yl] acetate
Clinical data
Legal status	CA: Schedule I; DE: Anlage I (Controlled); US: Schedule I;
Identifiers
CAS Number	1553-31-7
ATC code	None
ChEMBL	CHEMBL2107793
Chemical data
Formula	C23H31NO2
Molecular mass	353.5034 g/mol
	SMILES CC[C@H](C(C[C@H](C)N(C)C)(c1ccccc1)c2ccccc2)OC(=O)C.CC[C@@H](C(C[C@@H](C)N(C)C)(c1ccccc1)c2ccccc2)OC(=O)C ;
	InChI InChI=InChI=1S/2C23H31NO2/c21-6-22(26-19(3)25)23(17-18(2)24(4)5,20-13-9-7-10-14-20)21-15-11-8-12-16-21/h27-16,18,22H,6,17H2,1-5H3/t2*18-,22+/m10/s1 ; Key:HYAUQUUCBMIXJW-UAILNNRFSA-N ;

Alphacetylmethadol (INN), or α-acetylmethadol (AAM), is a synthetic opioid analgesic.^[2] Its levorotary enantiomer, levacetylmethadol, is an FDA-approved treatment for opioid addiction.^[2] Alphacetylmethadol is very similar in structure to methadone, a widely-prescribed treatment for opioid addiction. In the United States, it is a Schedule I controlled substance under the Controlled Substances Act (presumably because it was never marketed in the US, as is the case with other common opiate/opioid medications such as diacetylmorphine and alphaprodine), with an ACSCN of 9603 and a 2013 annual manufacturing quota of 2 grammes.^[3]

References

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