Perflubron

Perflubron

File:Perflubron structure.svg
Systematic (IUPAC) name
1-Bromo-1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluorooctane
Identifiers
CAS Number	423-55-2
ATC code	V08CX01 (WHO)
PubChem	CID: 9873
ChemSpider	9489
ChEMBL	CHEMBL1200866
Chemical data
Formula	C8BrF17
Molecular mass	498.96 g/mol
SMILES FC(F)(C(F)(F)C(Br)(F)F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F
InChI InChI=1S/C8BrF17/c9-7(22,23)5(18,19)3(14,15)1(10,11)2(12,13)4(16,17)6(20,21)8(24,25)26 Key:WTWWXOGTJWMJHI-UHFFFAOYSA-N
Physical data
Density	1.93 g/cm3
Melting point	6 °C (43 °F)
Boiling point	142 °C (288 °F)

Perflubron (INN/USAN, or perfluorooctyl bromide; brand name Imagent) is a contrast medium for magnetic resonance imaging, computer tomography and sonography. It was approved for this use in the United States by the Food and Drug Administration in 1993.

Experimental research

Perflubron has also been tested experimentally for use in liquid breathing in premature infants with respiratory distress.

See also Liquid breathing#Medical treatment for more information on this potential application.

File:Molecular ball-and-stick model of Perflubron, overlayed with electron-denisty coded VdW model.png

This molecular model of Perflubron is color-coded by electron density to illustrate the positive polarisation of the large bromine atom by the inductively electron-withdrawing perfluorooctyl chain.