Flosequinan

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Flosequinan
File:Flosequinan.svg
Systematic (IUPAC) name
(RS)-7-fluoro-3-methanesulfinyl-1-methyl-1,4-dihydroquinolin-4-one
Identifiers
CAS Number 76568-02-0 YesY
ATC code C01DB01 (WHO)
PubChem CID: 4474062
ChemSpider 3672315 N
UNII 6NB119DLU7 YesY
KEGG D04195 YesY
Chemical data
Formula C11H10FNO2S
Molecular mass 239.267 g/mol
  • CN1C=C(C(=O)C2=C1C=C(C=C2)F)S(=O)C
  • InChI=1S/C11H10FNO2S/c1-13-6-10(16(2)15)11(14)8-4-3-7(12)5-9(8)13/h3-6H,1-2H3 N
  • Key:UYGONJYYUKVHDD-UHFFFAOYSA-N N
 NYesY (what is this?)  (verify)

Flosequinan is a quinolone vasodilator. It has direct relaxing effects on peripheral arteries and veins. It is administered orally in cases of congestive heart failure in patients who are not responsive to digitalis or ACE inhibitors. It was sold under the trade name Manoplax.

It was withdrawn from the US market in October 1993 due to an increased risk of hospitalization or death.[1]

References

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