CD6

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Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). CD6 (Cluster of Differentiation 6) is a human protein encoded by the CD6 gene.[1][2]

Function

This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation.[1]

Clinical significance

Certain alleles of this gene may be associated with susceptibility to multiple sclerosis.[3][4]

See also

References

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Further reading

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External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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