Bendazac

Bendazac

Systematic (IUPAC) name
[(1-benzyl-1H-indazol-3-yl)oxy]acetic acid
Clinical data
AHFS/Drugs.com	International Drug Names
Routes of administration	Topical
Identifiers
CAS Number	20187-55-7
ATC code	M02AA11 (WHO) S01BC07
PubChem	CID: 2313
ChemSpider	2223 Y
UNII	G4AG71204O Y
KEGG	D01594 Y
ChEBI	CHEBI:31257
ChEMBL	CHEMBL1089221 Y
Chemical data
Formula	C16H14N2O3
Molecular mass	282.294 g/mol
SMILES O=C(O)COc2nn(c1ccccc12)Cc3ccccc3
InChI InChI=1S/C16H14N2O3/c19-15(20)11-21-16-13-8-4-5-9-14(13)18(17-16)10-12-6-2-1-3-7-12/h1-9H,10-11H2,(H,19,20) Y Key:BYFMCKSPFYVMOU-UHFFFAOYSA-N Y
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Bendazac (or bendazolic acid) is a non-steroidal anti-inflammatory drug used for joint and muscular pain.

Synthesis

Principle action is inhibition of protein denaturation.

Bendazac synthesis: BE 699226 ; G. Palazzo, U.S. Patent 3,470,194 (1967, 1969 both to Francesco Angelini).

Use of chloroacetamide in the alkylation step, followed by acid hydrolysis produces bendazac (instead of benzydamine).

See also

• Benzydamine