Transcription elongation regulator 1
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Transcription elongation regulator 1, also known as TCERG1, is a protein which in humans is encoded by the TCERG1 gene.[1][2][3]
Function
This gene encodes a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. The encoded protein interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. Alternative splicing results in multiple transcripts variants encoding different isoforms.[1]
Interactions
Transcription elongation regulator 1 has been shown to interact with SF1[4] and POLR2A.[5]
References
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Further reading
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