Avihepadnavirus
| Avihepadnavirus | |
|---|---|
| Virus classification | |
| Group: |
Group VII (dsDNA-RT)
|
| Family: | |
| Genus: |
Avihepadnavirus
|
| Type Species | |
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Avihepadnavirus is a genus of viruses, in the family Hepadnaviridae. Birds serve as natural hosts. There are currently only two species in this genus including the type species Duck hepatitis B virus. Diseases associated with this genus include: hepatitis, hepatocellular carcinomas (chronic infections), cirrhosis.[1][2][3]
Taxonomy
Group: ssRNA-RT
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Family: Hepadnaviridae
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Genus: Avihepadnavirus
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Structure
Viruses in Avihepadnavirus are enveloped, with spherical geometries, and T=4 symmetry. The diameter is around 42 nm. Genomes are circular, around 3.2kb in length. The genome codes for 7 proteins.[1]
| Genus | Structure | Symmetry | Capsid | Genomic Arrangement | Genomic Segmentation |
|---|---|---|---|---|---|
| Avihepadnavirus | Icosahedral | T=4 | Non-Enveloped | Circular | Monopartite |
Life Cycle
Viral replication is nucleo-cytoplasmic. Replication follows the dsDNA(RT) replication model. Dna templated transcription, specifically dsdna(rt) transcription, with some alternative splicing mechanism is the method of transcription. Translation takes place by ribosomal shunting. The virus exits the host cell by budding, and nuclear pore export. Birds serve as the natural host. Transmission routes are parental, sexual, and blood.[1]
| Genus | Host Details | Tissue Tropism | Entry Details | Release Details | Replication Site | Assembly Site | Transmission |
|---|---|---|---|---|---|---|---|
| Avihepadnavirus | Birds | Hepatocytes | Cell receptor endocytosis | Budding | Nucleus | Cytoplasm | Vertical: parental; sex; blood |
