FKBP2
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). FK506-binding protein 2 is a protein that in humans is encoded by the FKBP2 gene.[1][2]
Function
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. This gene has two alternatively spliced transcript variants that encode the same isoform. Multiple polyadenylation sites have been described for this gene, but the full length nature of this gene has not been determined.[2]
Interactions
FKBP2 has been shown to interact with ARFGEF1[3] and EPB41L2.[4]
References
Further reading
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