adipocyte protein 2
From Infogalactic: the planetary knowledge core
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| Fatty acid-binding protein, adipocyte | |||||||||||||
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Crystallographic structure adipocyte lipid-binding protein (PDB 2hnx) with palmitic acid (white sticks)[1]
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| Identifiers | |||||||||||||
| Symbols | FABP4 ;A-FABP, AFABP | ||||||||||||
| External IDs | OMIM: 600434 HomoloGene: 36067 IUPHAR: 2534 ChEMBL: 2083 GeneCards: FABP4 Gene | ||||||||||||
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| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 2167 | 11770 | |||||||||||
| Ensembl | n/a | n/a | |||||||||||
| UniProt | P15090 | P04117 | |||||||||||
| RefSeq (mRNA) | NM_001442 | NM_024406 | |||||||||||
| RefSeq (protein) | NP_001433 | NP_077717 | |||||||||||
| Location (UCSC) | n/a | n/a | |||||||||||
| PubMed search | [1] | [2] | |||||||||||
aP2 (adipocyte Protein 2)[2] is a carrier protein for fatty acids that is primarily expressed in adipocytes and macrophages. aP2 is also called fatty acid binding protein 4 (FABP4). Blocking this protein either through genetic engineering or drugs[3][4] has the possibility of treating heart disease,[5] diabetes,[6] asthma,[7] obesity,[8] and fatty liver disease.[9]
See also
References
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ Forbes health article July 14, 2006
- ↑ Medicinenet.com
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
External links
- FABP4 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
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