5-nitrosalicylate dioxygenase

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5-nitrosalicylate dioxygenase
Identifiers
EC number 1.13.11.64
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

5-nitrosalicylate dioxygenase (EC 1.13.11.64, naaB (gene)) is an enzyme with systematic name 5-nitrosalicylate:oxygen 1,2-oxidoreductase (decyclizing).[1][2] This enzyme catalyses the following chemical reaction

5-nitrosalicylate + O2 \rightleftharpoons 2-oxo-3-(5-oxofuran-2-ylidene)propanoate + nitrite (overall reaction)
(1a) 5-nitrosalicylate + O2 \rightleftharpoons 4-nitro-6-oxohepta-2,4-dienedioate
(1b) 4-nitro-6-oxohepta-2,4-dienedioate \rightleftharpoons 2-oxo-3-(5-oxofuran-2-ylidene)propanoate + nitrite (spontaneous reaction)

The enzyme from soil bacterium Bradyrhizobium sp. JS329 participates in 5-nitroanthranilate degradation.

References

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External links