Tetrahydroxynaphthalene reductase
From Infogalactic: the planetary knowledge core
(Redirected from EC 1.1.1.252)
| tetrahydroxynaphthalene reductase | |||||||||
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| Identifiers | |||||||||
| EC number | 1.1.1.252 | ||||||||
| CAS number | Template:CAS | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / EGO | ||||||||
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In enzymology, a tetrahydroxynaphthalene reductase (EC 1.1.1.252) is an enzyme that catalyzes the chemical reaction
- scytalone + NADP+
1,3,6,8-tetrahydroxynaphthalene + NADPH + H+
Thus, the two substrates of this enzyme are scytalone and NADP+, whereas its 3 products are 1,3,6,8-tetrahydroxynaphthalene, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is scytalone:NADP+ Delta5-oxidoreductase.
Structural studies
As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes 1DOH, 1G0N, and 1G0O.
References
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