1-Amino-2-propanol

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1-Amino-2-propanol
Aminopropanol.svg
Names
IUPAC name
1-Aminopropan-2-ol
Other names
Isopropanolamine
Monoisopropanolamine
MIPA; Threamine
Identifiers
78-96-6 YesY
Abbreviations MIPA
ChEBI CHEBI:19030 N
ChEMBL ChEMBL326602 YesY
ChemSpider 3 YesY
EC Number 220-532-9
Jmol 3D model Interactive image
KEGG C05771 YesY
PubChem 4
UNII UE40BY1BZW YesY
  • InChI=1S/C3H9NO/c1-3(5)2-4/h3,5H,2,4H2,1H3 YesY
    Key: HXKKHQJGJAFBHI-UHFFFAOYSA-N YesY
  • InChI=1/C3H9NO/c1-3(5)2-4/h3,5H,2,4H2,1H3
    Key: HXKKHQJGJAFBHI-UHFFFAOYAP
  • OC(C)CN
Properties
C3H9NO
Molar mass 75.11 g·mol−1
Appearance liquid
Odor ammonia-like
Density 0.973 g/mL (18 °C) [1]
Melting point 1.74 °C (35.13 °F; 274.89 K)
Boiling point 159.46 °C (319.03 °F; 432.61 K)
soluble
Solubility soluble in alcohol, ether, acetone, benzene, CCl4
1.4479
Vapor pressure {{{value}}}
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YesYN ?)
Infobox references

1-Amino-2-propanol (isopropanolamine) is a chemical compound with the formula C3H9NO. It is an amino alcohol. The term "isopropanolamine" may also refer more generally to the additional homologs diisopropanolamine (DIPA) and triisopropanolamine (TIPA).

It can be prepared by the addition of aqueous ammonia to propylene oxide.

Applications

The isopropanolamines are basic chemicals that can be used in many applications to achieve basicity, buffering and alkalinity objectives. They are good solubilizers of oil and fat, so they are used to neutralize fatty acids and sulfonic acid-based surfactants.

1-Amino-2-propanol is typically used in metal working fluid, waterborne coating, personal care products, and in the production of titanium dioxide and polyurethanes.[2]

1-Amino-2-propanol is an intermediate in the synthesis of a variety of pharmaceutical drugs and is the very basic building block of the opioid methadone.

The chemical derivative 1-dimethylamino-2-propanol can be synthesized via Eschweiler-Clarke methylation of 1-amino-2-propanol using formic acid and formaldehyde.[citation needed]

See also

References

  1. Amino-2-propanol at Sigma-Aldrich
  2. Lua error in package.lua at line 80: module 'strict' not found.