Epstein–Barr virus viral-capsid antigen
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The Epstein–Barr virus viral-capsid antigen (EBV-VCA) is the viral protein that forms the viral capsid of the Epstein–Barr virus. It is the antigen targeted by anti-VCA antibodies.[clarification needed] Such antibodies can be used in serology to diagnose infectious mononucleosis. In cases with primary infection, the sensitivity of IgG (immunoglobulin)[clarification needed] and IgM[clarification needed] anti-VCA testing has been estimated to be 100% reliable.[1]
Elevated Anti-VCA IgM indicates acute infection.
Elevated Anti-VCA IgG indicates prior infection.
References
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